Real World Evidence is here

Historically, decisions about drug efficacy and safety prior to launch have been driven strictly by the results of randomized controlled trials (RCTs). Today, however, evidence from real-world settings (outside of clinical trials) is more widely available, partly as a result of Healthcare’s move to a “pay for performance” model. Real World Evidence includes insurance reimbursement data, pharmacy data, Electronic Health Record (EHR) data, and patient-powered data.

And yet…

According to Dr. Jennifer Graff, Director of Comparative Effectiveness Research at the National Pharmaceutical Council, only 1 in 3 Managed Care organizations consistently use real-world evidence to inform their decisions.

Managed Care Organizations are not the only ones struggling to make sense of Real World Evidence. Pharmaceutical companies, government agencies, payers and providers are faced with the challenges of understanding the evidence, analyzing it, and, more importantly, driving decisions based on it.

The question is why. What are the barriers to using Real World Evidence?